In 1980, Vandross created some songs of his and own and by the chance of fame took them to Epic Records, thankfully he was granted a contract immediately upon playing his records. Epic released Vandross’s first solo album,” Never Too Much”, in 1981 . The album sold more than one million copies, cracked the top ten on black pop charts, and launched Vandross’s career as a solo superstar.” Vandross then released his follow-up album, ” For Ever, For Always, For Love”, one year later. All of his albums did tremendously well reaching number one on the R&B charts. Over the years Luther had the opportunity to produce hit albums for Cheryl Lynn in 1982, “Instant Love”, as time went by produced songs and/or albums for starts like Diana Ross, Aretha Franklin, and Whitney Houston.

In April , 2003 Vandross suffered a debilitating stroke that left him in a temporary coma. Doctors said the reason for his stroke was the combination of his recent weight gain and his ongoing struggle with diabetes. While the recovery was slow and difficult , six months after the stroke he gained the ability to speak and sing, but he was confined to a wheelchair and remained weak. He was unable to attend the 2003 Grammy Awards, however “Dance with My Father” was honored with four Grammys, including an award for Song of the Year. “The Grammy ceremony included a tribute to Vandross performed by Alicia Keys and Celine Dion. In a taped appearance, Vandross made his first public statement, telling fans:” I wish I could be with you there tonight. I want to thank everyone for your love and support. And remember, when I say goodbye it’s never for long, because I believe in the power of love.”